منابع مشابه
Skeletal Dysplasias: Growing Therapy for Growing Bones
Skeletal dysplasias represent a large and diverse group of rare conditions affecting collagen and bone. They can be clinically classified based on radiographic and physical features, and many can be further defined at a molecular level (Bonafe et al., 2015). Early diagnosis is critical to proper medical management including pharmacologic treatment when available. Patients with severe skeletal d...
متن کاملDeveloping bones are differentially affected by compromised skeletal muscle formation
Mechanical forces are essential for normal adult bone function and repair, but the impact of prenatal muscle contractions on bone development remains to be explored in depth in mammalian model systems. In this study, we analyze skeletogenesis in two 'muscleless' mouse mutant models in which the formation of skeletal muscle development is disrupted; Myf5(nlacZ/nlacZ):MyoD(-/-) and Pax3(Sp/Sp) (S...
متن کاملAdeshina Et Al.: Carpal Bones for Skeletal Maturity of Infants
We compare the utility of models of the structure of carpal bones in the hand for predicting skeletal maturity in infants (0 -7 yrs). Skeletal maturity assessment is important for diagnosing and monitoring growth disorders. Statistical models of bone shape and appearance have been shown to be useful for estimating skeletal maturity. In this work we investigate the effect of the choice of models...
متن کاملNo Bones About It: Insulin Modulates Skeletal Remodeling
Advancing the hypothesis that bone remodeling is intimately linked to metabolic homeostasis, Fulzele et al. (2010) and Ferron et al. (2010) present evidence that insulin signaling promotes the activation of bone-forming osteoblasts and enhances production of osteocalcin, a secreted mediator of insulin sensitivity, through modulation of bone resorption.
متن کاملAge determination on long bones in a skeletal subadults sample (b-12 years).
The skeletal age on the basis of the diaphyseal length of long bones was assessed. To this aim a sample of subadults skeleton, dated to last century, coming from the cemetery of Bologna was studied. The sample is composed by 79 males and 70 females between 0 and 12 years, whose chronological age and sex are known. Some information can be obtained by the means, standard deviation and graphs of t...
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ژورنال
عنوان ژورنال: Genetics in Medicine
سال: 2000
ISSN: 1098-3600,1530-0366
DOI: 10.1097/00125817-200001000-00040